I've only been scootering for 16 months and m/c riding for 8 months, but that's after 35 yrs of cycling (transportation and recreation). Was wary about the higher speeds involved, but in many ways that makes it safer than pedaling. I'm surprised at how safe 2 wheel motoring feels. Much safer than it looks.
There is no substitute for situational awareness and anticipation. And visibility! Would never tell anyone not to wear protective gear, however I'm perfectly comfortable w ¾ helmet, gloves, sneakers and regular pants and shirt, white or bright colored.
Using peripheral vision, especially at intersections, and regularly checking the rear view mirror goes a long way to preventing collisions. Got to know who's behind you to maximize anticipation. Keeping your distance (find the gap), expecting sudden stops and un-signaled turns/lane changes, and riding as though you're invisible has all helped in making me feel safe out there. But that's probably obvious to all you seasoned riders.