My Fiat van has specs for different loads (up to 2000lbs+) and the differences in tire pressures are rather big.
Hmmm...going back to your original question referring to the DT300 manual. Maybe its a general statement by Kymco in their manuals because they will never know what brand, speed rating, or load rating your next tire would be or the tire that will become OEM of Kymco when they created the manual. Different countries even use different brands of tires for a single scooter model. Maybe the best thing is to get information from the tire and not from the manual. My manual is even incomplete, I have to search the net (forums) to find out how to set the clock of the Super 8. Turned out its very difficult to do.
I think tire manufacturers are aware of all the beatings a tire gets... rocks, gravel, heat, oil/gasoline, UV rays, water, mud, cornering flexes, hard brakings, acceleration, load, speed, etc. A good brand of tire with the right specs and preferred tire pressure, I think, would be safe.