First visually inspect to make sure all the lines are connected to their source. An old shade tree mechanic trick is to get some carb cleaner and spray the lines in short, directed bursts, paying particular attention to the ends. Also spray where the intake boot meets the intake. If there is a leak, the cleaner will be sucked into to the system and you will notice a change in idle. Do be careful though, obviously carb cleaner is flammable. Do not spray near the spark plug or the exhaust. There are youtube vids on this if you need further instructions. As far as your mixture screw, just check to make sure it hasn't backed out.