Right - you can absolutely feel the difference in oils, and the smaller the engine, the more pronounced it is.
Used to run a C90 on no-brand 10w-40 and it hated it. Switched to Motul 10w-40 (still mineral) and it was much happier.
The 4-stroke 50cc CVTs I've had (quite a lot, got a soft spot for them for sure) absolutely purr on fully synthetic oil compared to semi-synth or mineral. You can hear it running more smoothly at tickover, and feel it in engine vibes through the seat.
I've now just confirmed myself as an oil nerd