You do technically lose potential top end speed that you would probably never reach with the OEM rollers.
The trick is that you really will reach the actual top end with the lighter ones.
DPs vs. rollers. I have two almost identical bikes, & ran 1g light sliders and rollers in 'em side by side.
1g lighter was definitely the right thing for this bike (SYM HD200), but there was marked difference throughout the range with the rollers vs. sliders.
As you'd expect the top end with the rollers was definitely getting pretty revved up, but the sliders really aren't too bad.
Off the line. The punch of the rollers was markedly different from and a bit quicker than the sliders.
MPG - sliders are enough better to notice but not enough better to worry about much.
After running 'em like that for a bit I eventually bought a second set of sliders.
Of note, on my old S200 even running OEM weight DP sliders eliminated the annoying dead spot it had in the 30-35 mph range.
...He said I was dead wrong. That a lighter weight roller will improve both the acceleration and the top speed.
anyway - you won't know if those weights will suit your riding style, unless you try them.
Stig